499 A Retrospective Audit on Detection Rate of Clinically Significant Cancer Among MP-MRI Targeted Biopsy – A Single Centre Experience

Abstract Men with high serum prostate specific antigen (PSA) typically undergo standard transrectal ultrasound-guided biopsy (TRUS-biopsy) during which 10 to 12 cores are obtained. TRUS-biopsy can cause side-effects including bleeding, pain, and infection. Multi-parametric MRI (MP-MRI) used as a triage test might allow men avoid unnecessary improve diagnostic accuracy. According the renowned PROMIS study, for clinically significant cancer, MP-MRI was more sensitive less than TRUS-biopsy. In this we performed single centre, retrospective audit on detection rate of cancer among targeted compare it TRUS biopsy. Clinically is defined Gleason score ³ 4 +3 or maximum core length 6mm longer. Besides, also in against study. Through audit, found that 2019, there 54% (60 out 112 patients) 41% (26 64 Comparing study detected 38% group 26% standard-biopsy group, adjusted difference our (13%) similar 12%. conclusion, reaffirms reduce over-diagnosis insignificant cancer.